Gene interactions and pathways from curated databases and text-mining

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EIF2AK2 — IL10

Text-mined interactions from Literome

Chakrabarti et al., J Biol Chem 2008 : Here we show PKR regulates interleukin-10 induction in response to double stranded RNA, bacterial lipopolysaccaride, and Sendai virus infection ... Using chemical inhibitors, dominant negative constructs, and genetic knockouts, we demonstrate that the PKR mediated interleukin-10 induction engages JNK and NF-kappaB
Pereira et al., FASEB J 2010 : PKR activation induced by dsRNA also resulted in IL-10 production, whose neutralization with specific antibody completely abrogated L. amazonensis proliferation
Lin et al., Cytokine 2010 : A role for protein kinase PKR in the mediation of Epstein-Barr virus latent membrane protein-1 induced IL-6 and IL-10 expression