Gene interactions and pathways from curated databases and text-mining

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CD40LG — FCER2

Text-mined interactions from Literome

Sukumar et al., J Immunol 2006 : Differences in murine follicular dendritic cells ( FDC ) -CD23 expression under Th1 vs Th2 conditions prompted the hypothesis that T cells help regulate the phenotype of FDCs. FDCs express CD40, suggesting that T cell-CD40L and lymphokines may be involved in regulating FDC-CD23 ... Previous studies suggest that high levels of FDC-CD23 inhibit IgE production, and this IFN-gamma and CD40L mediated up-regulation of FDC-CD23 may explain, at least in part, why Th1 responses are associated with low IgE responses in vivo
Burlinson et al., Eur J Immunol 1996 : Soluble CD40 ligand induces expression of CD25 and CD23 in resting human tonsillar B lymphocytes
Richards et al., J Immunol 1997 (Lymphoma) : IL-4 and CD40 ligand stimulate transcription of CD23 ( Fc epsilonRII ) in B cells and are necessary for the expression of germline epsilon mRNA and production of IgE