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CASP8 — CXCL17

Text-mined interactions from Literome

Chen et al., Mol Pharmacol 2007 (Carcinoma, Non-Small-Cell Lung...) : To determine the underlying mechanism of the synergy between DMC and TRAIL, we have demonstrated that DMC induces a CCAAT/enhancer binding protein homologous protein dependent expression of DR5, a major TRAIL receptor, and reduces the levels of cellular FLICE-inhibitory protein ( c-FLIP ) ( both the long and short forms ), key inhibitors of death receptor mediated apoptosis, by facilitating c-FLIP degradation through a ubiquitin/proteasome dependent mechanism
Huang et al., J Sci Food Agric 2012 (Disease Models, Animal...) : DMC could also increase 5-FU concentrations in tumor tissues and increase caspase-3 activity