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CD74 — EPHB2
Text-mined interactions from Literome
Kamir et al., J Immunol 2008
:
Like its mammalian counterpart, Lm1740MIF induces
ERK1/2 MAP kinase activation in a
CD74 dependent manner and inhibits the activation induced apoptosis of macrophages
Sekiguchi et al., Biosci Biotechnol Biochem 2010
(Stomach Neoplasms) :
Suppression of
CD74 expression and Helicobacter pylori adhesion by auraptene targeting serum starvation
activated ERK1/2 in NCI-N87 gastric carcinoma cells
Lv et al., Clin Sci (Lond) 2013
(Anti-Glomerular Basement Membrane Disease) :
These changes were associated with up-regulation of MIF and its receptor
CD74 activation of
ERK ( extracellular-signal regulated kinase ) and NF-?B ( nuclear factor ?B ) signalling, prominent macrophage and T-cell infiltration, as well as up-regulation of Th1 [ T-bet and IFN? ( interferon ? ) ] and Th17 [STAT3 ( signal transducer and activator of transcription 3 ) and IL ( interleukin)-17A ] as well as IL-1ß and TNFa ( tumour necrosis factor a )