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EPHB2 — GPR34
Text-mined interactions from Literome
Cao et al., J Biol Chem 2000
:
Together, these data describe a novel mechanism of
ERK activation by a
G protein coupled receptor in which the intracellular domains directly recruit c-Src
Baens et al., Haematologica 2012
(Lymphoma, B-Cell, Marginal Zone...) :
Although functional consequences of t ( X ; 14 ) have not been identified, our studies suggest that up-regulated
GPR34 activate neither nuclear factor-?B nor
ELK related tyrosine kinase
Ansell et al., Blood 2012
(Lymphoma, B-Cell, Marginal Zone...) :
Overexpression of
GPR34 in lymphoma and HeLa cells
resulted in phosphorylation of
ERK , PKC, and CREB ; induced CRE, AP1, and NF-?B mediated gene transcription ; and increased cell proliferation