Gene interactions and pathways from curated databases and text-mining

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EPHB2 — GPR34

Text-mined interactions from Literome

Cao et al., J Biol Chem 2000 : Together, these data describe a novel mechanism of ERK activation by a G protein coupled receptor in which the intracellular domains directly recruit c-Src
Baens et al., Haematologica 2012 (Lymphoma, B-Cell, Marginal Zone...) : Although functional consequences of t ( X ; 14 ) have not been identified, our studies suggest that up-regulated GPR34 activate neither nuclear factor-?B nor ELK related tyrosine kinase
Ansell et al., Blood 2012 (Lymphoma, B-Cell, Marginal Zone...) : Overexpression of GPR34 in lymphoma and HeLa cells resulted in phosphorylation of ERK , PKC, and CREB ; induced CRE, AP1, and NF-?B mediated gene transcription ; and increased cell proliferation