Gene interactions and pathways from curated databases and text-mining

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DUSP9 — EPHB2

Text-mined interactions from Literome

Kar-Roy et al., J Biol Chem 2004 : This is the first example of a viral protein regulating ERK activation by inhibition of its cognate dual specificity phosphatase
Hu et al., Mol Cell Biol 2006 (Lung Neoplasms) : While activated ERK phosphorylates Hsf4b, DUSP26 controls the activity of ERK , leading to phosphorylation/dephosphorylation of Hsf4b, altering its ability to bind DNA
Emanuelli et al., Proc Natl Acad Sci U S A 2008 (Insulin Resistance) : Overexpression of MKP-4 in 3T3-L1 cells inhibited ERK and JNK phosphorylation and, to a lesser extent, p38MAPK phosphorylation
Li et al., Cell stem cell 2012 : Through DUSP9 mediated inhibition of ERK activity, BMP signaling reinforces the self-renewal status of mouse ESCs together with LIF
Maloney et al., Am J Physiol 1999 : ANG II-induced activations of Fyn, Raf-1, and ERK were augmented in cells pretreated with BAPTA-AM, but ANG II-induced expression of the dual-specificity phosphatase mitogen activated protein kinase phosphatase-1 was blocked by BAPTA-AM pretreatment