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PI3 — WNK1
Text-mined interactions from Literome
Vitari et al., Biochem J 2004
(Hypertension...) :
Consistent with PKB mediating this phosphorylation, inhibitors of
PI 3-kinase ( phosphoinositide 3-kinase ; wortmannin and LY294002 ) but not inhibitors of mammalian target of rapamycin ( rapamycin ) or MEK1 ( mitogen activated protein kinase kinase-1 ) activation ( PD184352 ),
inhibited IGF1 induced phosphorylation of endogenous
WNK1 at Thr-60
Liu et al., Eur J Pharmacol 2013
:
Furthermore, a
phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 significantly
suppressed LPS induced NF-?B
p65 nuclear translocation, iNOS expression, and NO production, which was also mimicked by pretreatment with DSC