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NOD1 — TNF
Text-mined interactions from Literome
van Heel et al., Eur J Immunol 2005
:
NOD1 activation by low nanomolar concentrations of the specific muropeptide ligand M-TriDAP
induced minimal human peripheral blood mononuclear cell
TNF-alpha , IL-1beta or IL-10 secretion, but synergistically increased Toll-like receptor ( TLR ) -induced responses
Masumoto et al., J Exp Med 2006
:
Nod1 stimulation did not
induce TNFalpha , interleukin 12, and interferon gamma, suggesting that the primary role of Nod1 is to induce the recruitment of immune cells
de Jong et al., PLoS Pathog 2012
(Salmonella Infections...) :
The interaction of Salmonella pathogen associated molecular patterns ( PAMPs ) with Toll-like receptors ( TLRs ) and
NOD-like receptors ( NLRs ) leads to inflammasome formation, activation, and recruitment of neutrophils and macrophages and the production of pro-inflammatory cytokines, most notably interleukin (IL)-6, IL-1ß,
tumor necrosis factor (TNF)-a , and interferon-gamma (IFN)-?