Gene interactions and pathways from curated databases and text-mining

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STAT1 — TIMP1

Text-mined interactions from Literome

Liu et al., Zhonghua Yi Xue Za Zhi 2001 : STAT1 and STAT3 antisense oligonucleotides inhibited both STAT DNA binding activity and TIMP1 mRNA expression in mesangial cells
Chen et al., Kidney Int 2002 : STAT1 and STAT3 mediate thrombin induced expression of TIMP-1 in human glomerular mesangial cells ... EMSA showed that STAT1 and STAT3 antisense oligonucleotides could inhibit both thrombin induced STAT-DNA binding activities and TIMP-1 mRNA expression ; the supershift assay showed that the SIF band consisted of STAT1 and STAT3 proteins ... Both STAT1 and STAT3 may be involved , at least in part, in thrombin induced expression of the TIMP-1 gene in cultured human mesangial cells
Chen et al., Kidney Int 2003 : Northern and Western blots showed that STAT1 and STAT3 antisense oligonucleotides could inhibit angiotensin II-induced TIMP-1 expressions, and STAT1 and STAT3 proteins, respectively, could be supershifted by their polyclonal antibodies ... STAT1 and STAT3 may, at least in part, mediate angiotensin II-induced TIMP-1 mRNA expression in human renal proximal tubular epithelial cells, implicating a role of the STAT signaling pathway in pathogenesis of renal tubulointerstitial fibrosis