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DDR1 — NPPA

Text-mined interactions from Literome

Lainchbury et al., J Clin Endocrinol Metab 1999 (Ventricular Dysfunction, Left) : Endogenous plasma ANP was augmented more than BNP by NEP inhibition
Corti et al., Circulation 2001 (Cardiovascular Diseases) : Inhibition of NEP increases levels of atrial natriuretic peptide (ANP) , brain natriuretic peptide ( BNP ) of myocardial cell origin, and C-type natriuretic peptide (CNP) of endothelial cell origin as well as bradykinin and adrenomedullin
Mtairag et al., Arterioscler Thromb Vasc Biol 2002 (Anoxia) : ANP alone and its potentiation by retrothiorphan, the NEP inhibitor , significantly inhibited superoxide, lysozyme, and matrix metalloproteinase (MMP)-9 release by N-formyl-Met-Leu-Phe stimulated PMNs. Activated PMNs degraded exogenous ANP, which was prevented by NEP inhibition
Lindberg et al., Regul Pept 1992 : Beside renal clearance, an extra-renal metabolism by the enzyme neutral endopeptidase-24.11 ( NEP-24.11 ) has been proposed, since specific NEP-24.11-inhibitors increase endogenous plasma-ANP
Nagatomo et al., Biochem Biophys Res Commun 1996 : The present data suggest that NEP may be involved in the circulation control by degrading PAMP as well as ANP