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ELF1 — IL2
Text-mined interactions from Literome
Greene et al., J Immunol 2000
(Sarcoidosis, Pulmonary) :
Examination of transcription factor activation and IL-2 gene expression in Jurkat T cells revealed that sarcoid but not normal
ELF activated AP1 and NF-kappaB, induced IL-2 gene transcription, and
up-regulated IL-2 protein production
Serdobova et al., J Exp Med 1997
:
In addition, by introducing mutations into the core of the site III Ets-like motif and comparing the corresponding effects on the in vitro binding of Elf-1 and the in vivo IL-2rE activity, we provide strong evidence that
Elf-1 is directly
involved in
IL-2 responsiveness