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RELA — TRAM2

Text-mined interactions from Literome

Li et al., J Mol Med (Berl) 2005 : LPS induced, TLR4 mediated signaling employs multiple TIR-domain containing adaptors, MyD88/TIRAP to mediate NFkappaB activation, TRIF/TRAM for IRF3 activation
Bulut et al., J Biol Chem 2005 (Inflammation) : Mycobacterial heat shock protein 65-induced NF-kappaB activation was MyD88-, TIRAP-, TRIF-, and TRAM dependent and required the presence of MD-2
Seki et al., Hepatology 2008 (Acute Disease...) : Toll-like receptors ( TLRs ) are pattern recognition receptors that recognize pathogen associated molecular patterns and signal through adaptor molecules, myeloid differentiation factor 88 ( MyD88 ), Toll/IL-1 receptor domain containing adaptor protein ( TIRAP ), Toll/IL-1 receptor domain containing adaptor inducing interferon-beta ( TRIF ), and TRIF related adaptor molecule ( TRAM ) to activate transcription factors, nuclear factor (NF)-kappaB , activator protein 1 (AP-1), and interferon regulatory factors ( IRFs ) leading to the initiation of innate immunity