Gene interactions and pathways from curated databases and text-mining

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NFKBIA — TNFSF10

Text-mined interactions from Literome

Milani et al., J Neurochem 2003 (Neuroblastoma) : At later time points ( from 3 to 6 h onwards ) TRAIL induced a progressive degradation of inhibitor of kappaB (IkappaB)beta and IkappaBepsilon, but not IkappaBalpha , coupled to the nuclear translocation of NF-kappaB and an increase in its DNA binding activity
Chen et al., Molecular cancer 2010 (Carcinoma, Non-Small-Cell Lung...) : Interestingly, knockdown of DR5, but not DR4, prevented GGTI298/TRAIL induced IkappaBalpha and p-Akt reduction, suggesting that DR5 mediates reduction of IkappaBalpha and p-Akt induced by GGTI298/TRAIL