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MAPK1 — MUC4
Text-mined interactions from Literome
McNamara et al., Am J Respir Cell Mol Biol 2006
:
The induction of
mucin by flagellin in human lung epithelial cells ( NCIH292 ) is
dependent on asialoGM1 ligation, ATP receptor signaling, Ca2+ mobilization, and
Erk1/2 activation
Ríos et al., Exp Eye Res 2008
(MAP Kinase Signaling System) :
The purpose of the study was to determine if OPC-12759 stimulates secretion from conjunctival goblet cells in culture and if it activates the EGF receptor (EGFR) and p44/p42
mitogen activated protein kinase ( MAPK ) to
cause mucin secretion
Román et al., Eukaryotic cell 2009
(Candidiasis) :
Msb2 signaling
mucin controls activation of Cek1
mitogen activated protein kinase in Candida albicans
Hodges et al., Exp Eye Res 2012
:
Inhibitors against the EGF receptor and
ERK 1/2 also
blocked Cch stimulated
mucin secretion
Mukhopadhyay et al., PloS one 2013
(Breast Neoplasms...) :
In addition, our studies demonstrated that
MUC4 up-regulates the EGFR family of proteins, and
augments downstream
Erk1/2 , PKC-?, and FAK mediated oncogenic signaling