Lachmann et al., Mol Biol Cell 2012
:
This ensures specificity of the subsequent GEF mediated activation of the Rab that initiates the next transport event
Levine et al., Bioinformatics 2013
(Amyotrophic Lateral Sclerosis...) :
Sensitive homology searches showed that C9ORF72 is a full-length distant homologue of proteins related to Differentially Expressed in Normal and Neoplasia ( DENN ), which is a GDP/GTP exchange factor (GEF) that activates Rab-GTPases