Gene interactions and pathways from curated databases and text-mining

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PCNA — RBBP7

Text-mined interactions from Literome

Clark et al., Exp Cell Res 2004 (Leukemia, Promyelocytic, Acute) : Combination 1,25 ( OH ) ( 2 ) D ( 3 ) and bryostatin-1 treatment, resulted in decreased expression of the cyclin dependent kinases Cdk2, Cdk1, and Cdk4, of cyclins E and D3, and of the retinoblastoma binding protein ( RBBP )
Hatjiharissi et al., Cancer Res 2007 (Waldenstrom Macroglobulinemia) : Other proteins up-regulated by > 1.3-fold included cyclin dependent kinases, apoptosis regulators, and histone deacetylases (HDAC)
Brett et al., Current treatment options in oncology 2013 : Similarly, cell cycle inhibitors targeting cyclin dependent kinases as well as HDAC inhibitors have shown promise in early studies