Gene interactions and pathways from curated databases and text-mining

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EPHB2 — SNAP25

Text-mined interactions from Literome

He et al., American journal of physiology. Renal physiology 2003 : SNP or SNAP had no significant effect on cellular levels of cGMP, cAMP, cytosolic calcium, or phosphorylation of ERK1 and ERK2
Xu et al., Am J Physiol Heart Circ Physiol 2004 (Heart Diseases...) : A Western blotting study showed that SNAP significantly enhanced phosphorylation of ERK , which was reversed by MPG
Jones et al., Biochem Biophys Res Commun 2004 : SNAP , at 0.5-4 mM, significantly and dose-dependently inhibited angiogenesis, PKC activity, and ERK and c-Jun phosphorylation up to 80 %, 83 %, and 63 % and 73 %, respectively
Palen et al., Cardiovasc Res 2005 : The basal interaction between ERK1/2 and SHP-1 was decreased in response to SNAP stimulation
Magalhães et al., Int J Dev Neurosci 2006 : Using purified cultures of glial cells we showed that the NO donor SNAP produced an inhibition of 50 % in cell proliferation and did stimulate ERK1/2 phosphorylation, indicating that the inhibition of this pathway was not involved in its cytostatic effect
Li et al., Apoptosis 2006 (Myocardial Reperfusion Injury) : However, treatment with U0126 completely blocked SNAP induced ERK activation and markedly, although not completely, inhibited the cardioprotection exerted by SNAP
Arai et al., Biochem Biophys Res Commun 2006 : Downstream to p21Ras, the MAP Kinases ERK1/2 were activated by SNAP under conditions that promote TRX-1 nuclear translocation ... Inhibition of MEK prevented SNAP stimulated ERK1/2 activation and TRX-1 nuclear migration