Gene interactions and pathways from curated databases and text-mining

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MMP7 — STAT3

Text-mined interactions from Literome

Udayakumar et al., Prostate 2004 (Prostatic Neoplasms) : Further, expression of dominant negative STAT3 inhibited the FGF-1 induced transactivation of the human MT1-MMP 7.2-kb promoter
Holnthoner et al., Biochem Biophys Res Commun 2006 : Instead, we show that overexpression of a dominant negative Stat3 mutant reduces FGF-2 mediated MMP7 promoter activity ... However, Stat3 does not bind to the MMP7 promoter, but activates MMP7 gene expression indirectly via AP-1
Pini et al., J Leukoc Biol 2012 (Inflammation...) : However, the delayed resolution of neutrophil infiltration ; sustained production of CXCL1, CXCL2, and CCL2 ; prolonged activation of STAT-3 ; and induction of MMP-7 in the pancreas, as well as heightened induction of serum amylase A of DIO mice, were blunted significantly in DIO IL-6 KO mice