Gene interactions and pathways from curated databases and text-mining

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HSP90AA1 — PCNA

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Lacey et al., Proc Natl Acad Sci U S A 1999 : Cyclin dependent kinase control of centrosome duplication
Singh et al., Mol Cell Biochem 2011 (Uterine Cervical Neoplasms) : Molecular studies showed elevation of Telomerase, viral oncoproteins E6 and E7, PCNA, p16, Cyclin D1 in HPV positive cell lines on treatment with estradiol but after treatment with curcumin the level of E7, PCNA , and Cyclin D1 was reduced but the level of E6, Telomerase , and p16 was unaltered
Pozo et al., Mol Cell Biol 2011 : Furthermore, Hsp90 inhibition disrupts the interaction between REV1 and monoubiquitinated PCNA and suppresses UV-induced focus formation
Arnaud et al., Chromosoma 1998 : In vertebrates, Plks participate in centrosome maturation and spindle assembly, as well as the activation of the Cdk1/cyclin B complex