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STAT1 — STAT4

Text-mined interactions from Literome

Farrar et al., J Biol Chem 2000 : Expression of murine Stat4 in the Stat1-deficient U3A and the Stat2-deficient U6A cell lines shows that IFN-alpha induced Stat4 phosphorylation requires the presence of activated Stat2 but not Stat1
Lieberman et al., J Immunol 2004 (Toxoplasmosis, Animal) : In addition, recent studies have suggested that the ability of STAT1 to inhibit the activation of STAT4 prevents the development of Th1 responses
Berenson et al., J Immunol 2006 : Furthermore, loss of STAT1 increases IFN-alpha induced STAT4 phosphorylation, but does not generate levels of STAT4 activation or IFN-gamma production achieved by IL-12 or convert transient STAT4 activation into a sustained response
Cui et al., J Biol Chem 2009 (Diabetes Mellitus, Type 1...) : Berberine down-regulated the activity of STAT1 and STAT4 through the suppression of p38 MAPK and JNK activation, and it controlled the stability of STAT4 through the ubiquitin-proteasome pathway