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HMOX1 — MAP2K1
Text-mined interactions from Literome
Ryter et al., Antioxid Redox Signal 2002
(MAP Kinase Signaling System) :
Surprisingly, SB203580, an inhibitor of p38 MAPK, and PD98059, an inhibitor of
mitogen activated protein kinase kinase ( MEK1 ), strongly
enhanced hypoxia induced
HO-1 mRNA expression in PAEC
Chen et al., Biochem Biophys Res Commun 2005
:
LY294002 and U0126, pharmacological inhibitors of phosphatidylinositol 3-kinase and
MEK1/2 which are upstream of Akt and ERK1/2, respectively,
attenuated resveratrol induced
HO-1 expression and exhibited antioxidant effects
Wu et al., Life Sci 2006
:
In addition, pharmacological inhibitors of phosphatidylinositol 3-kinase and
MEK1/2 , which are upstream of Akt and ERK1/2, respectively,
attenuate EGCG induced
HO-1 expression