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IL5 — NEUROD1
Text-mined interactions from Literome
Muroya et al., Oncogene 1992
:
In contrast, basic fibroblast growth factor,
interleukin 6 and dibutyryl cAMP, which
induce neuronal differentiation of PC12 cells, did not stimulate the accumulation of p21-GTP at any time point examined
Zhang et al., J Neurochem 2006
(Neuroblastoma) :
These findings demonstrate divergent molecular and physiological responses to telomere dysfunction in mitotic neural cells and neurons, indicate a
role for
TRF2 in regulating
neuronal differentiation , and suggest a potential therapeutic application of inhibition of TRF2 function in the treatment of neural tumors
Zhang et al., Proc Natl Acad Sci U S A 2011
:
Apart from protecting telomeres, nuclear
TRF2 interacts with the master neuronal gene-silencer repressor element 1-silencing transcription factor ( REST ), and disruption of this interaction
induces neuronal differentiation