Gene interactions and pathways from curated databases and text-mining

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CFL2 — CXCL12

Text-mined interactions from Literome

Nishita et al., Mol Cell Biol 2002 : Stromal cell derived factor 1alpha activates LIM kinase 1 and induces cofilin phosphorylation for T-cell chemotaxis ... SDF-1alpha also induced cofilin phosphorylation, actin reorganization, and activation of small GTPases, Rho, Rac, and Cdc42, in Jurkat cells ... Treatment of Jurkat cells with S3 peptide inhibited the SDF-1alpha induced cofilin phosphorylation, actin reorganization, and chemotactic response of Jurkat cells
Liberman et al., PloS one 2013 : Downstream in the PI-3 kinase signaling pathway, GLP-1 ( 9-36 ) inhibited SDF-1 induced phosphorylation of MLC and cofilin and decreased f-actin formation as well as ICAM3 translocation as shown by Western blotting, flow cytometry and immunohistochemistry, respectively