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IL12A — RNF19A

Text-mined interactions from Literome

Zhang et al., J Immunol 2000 : In this report we demonstrate that IL-12 activates mitogen activated protein kinase kinase 3/6 ( MKK ) and p38 mitogen activated protein kinase ( MAPK ), but not p44/42 ( ERK ) or stress activated protein kinase/c-Jun N-terminal kinase MAPK
Mavropoulos et al., Blood 2005 : Mitogen activated protein kinase p38 was activated strongly by IL-18 and weakly by IL-12 in natural killer cells but was not activated by either cytokine in T cells
Kitanaka et al., Biochem Biophys Res Commun 2006 : Collectively, it is suggested that E-FABP may be a novel negative regulator of IL-12 production in DCs, and this regulation may be exerted via its involvement in the p38MAPK mediated transcription of IL-12p35
Dobreva et al., Cytokine 2008 (MAP Kinase Signaling System) : The inhibition of both JNK and p38 augmented IL-12p40 production
Mitchell et al., J Infect Dis 2010 : IL-12p40 was significantly inhibited by both p38 mitogen activated protein kinase ( MAPK ) and extracellular signal regulated kinase inhibitors, whereas IL-12p70 was inhibited by p38 MAPK inhibitor alone
Rastogi et al., Am J Respir Crit Care Med 2011 (Sarcoidosis, Pulmonary) : Inhibition of p38 , but not ERK, attenuated production of both IL12/IL23p40 and TNF-a
Yang et al., J Immunol 2010 (Leishmaniasis) : We show that inhibition of p38 dramatically increased IL-12 production upon stimulation, while decreasing TNF-a
Katholnig et al., J Immunol 2013 : p38a signaling in myeloid immune cells promoted IL-10 but inhibited IL-12 expression via mTOR and blocked the differentiation of proinflammatory CD4 ( + ) Th1 cells