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CCND1 — TCF7L2

Pathways - manually collected, often from reviews:

• KEGG Wnt signaling pathway: LEF1/TCF7/TCF7L1/TCF7L2 → CCND1/CCND2/CCND3 (gene expression, expression)
• KEGG Pathways in cancer: LEF1/TCF7/TCF7L1/TCF7L2 → CCND1 (gene expression, expression)
• KEGG Colorectal cancer: LEF1/TCF7/TCF7L1/TCF7L2 → CCND1 (protein-protein, expression)
• KEGG Endometrial cancer: LEF1/TCF7/TCF7L1/TCF7L2 → CCND1 (gene expression, expression)
• KEGG Prostate cancer: LEF1/TCF7/TCF7L1/TCF7L2 → CCND1 (gene expression, expression)
• KEGG Thyroid cancer: LEF1/TCF7/TCF7L1/TCF7L2 → CCND1 (gene expression, expression)
• WikiPathways DNA Damage Response (only ATM dependent): TCF7/TCF7L1/TCF7L2/LEF1 → CCND2/FOSL1/CCND1/CCND3/MYC/JUN/PLAU (inhibition)
  

Text-mined interactions from Literome

Pradeep et al., Oncogene 2004 (Stomach Neoplasms) : In addition, G-17 mediated increase in cyclin D1 transcription was significantly attenuated by axin or dominant negative ( dn ) T-cell factor 4 ( TCF4 ) , suggesting crosstalk of G-17 with the Wnt signaling pathway
Wang et al., Int J Cancer 2009 (Carcinoma, Hepatocellular...) : It also inhibited the transcriptional activities of beta-catenin/TCF4 , and USF2, and inhibited the expression of endogenous cyclin D1 and TGFbeta2