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HSPG2 — IL6

Text-mined interactions from Literome

Morga et al., J Neurochem 2000 (Inflammation) : The IRL1620 induced increase of IL-6 is dependent on PLC activation
Rees et al., Br J Pharmacol 2003 : NECA mediated IL-6 release was inhibited by the PLC inhibitor 1- [ 6- ( ( 17beta-3-methoxyestra-1,3,5 ( 10 ) -tiene-17-yl ) amino ) hexyl ] -1H-pyrrole-2,5-dione, the PI3 kinase inhibitor wortmannin and the PKC inhibitors bisindolylmaleimide 1 and bisindolymaleimide X1 HCl ( Ro-32-0432 )
Kondo et al., Biochem Pharmacol 2004 (Osteosarcoma) : These findings suggest that BK increased both IL-6 and PGE ( 2 ) synthesis in osteoblastic cells via B2R and that PLC , IP ( 3 ) -induced [ Ca ( 2+ ) ] i, MEK, and MAPKs were involved in the signal transduction in these cells
Tschaikowsky et al., J Pharmacol Exp Ther 1998 (Shock, Septic) : Inhibition of PC-PLC by the specific inhibitor tricyclodecan-9-yl-xanthogenate ( D609 ) before LPS reduced the release of interleukin-1 beta, interleukin-6 and nitric oxide ( NO ) in vivo