Gene interactions and pathways from curated databases and text-mining

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CLU — HSPA5

Text-mined interactions from Literome

Li et al., Oncogene 2013 (Prostatic Neoplasms) : GRP78 regulates clusterin stability, retrotranslocation and mitochondrial localization under ER stress in prostate cancer
Wang et al., PloS one 2013 (Carcinoma, Hepatocellular...) : Knockdown of CLU expression in SMMC7721 and HCCLM3 cells inhibited GRP78 expression after TN treatment and enhanced ER stress induced apoptosis, whereas over-expression of CLU in HepG2 cells increased GRP78 expression after TN induction and abolished the effect of TN on cell apoptosis