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Text-mined interactions from Literome
Tsang et al., J Leukoc Biol 2005
(Inflammation...) :
Results indicated that
SCF activated
ERK , and TNF-alpha activated the p38 MAPK and NF-kappaB pathway ... Therefore,
SCF and TNF-alpha
acted through
ERK and the NF-kappaB pathway to regulate the ICAM-1 expression and elicited the synergistic effect
Khanzada et al., Oncogene 2006
(Carcinoma, Small Cell...) :
These responses correlated with the inhibition of
stem cell factor (SCF) stimulated activation of extracellular signal regulated kinase (
Erk ), protein kinase B (PKB) and ribosomal S6 kinase by simvastatin
Wong et al., Allergy 2006
:
The induction of RANTES by SCF or TNF-alpha was mediated by
ERK and NF-kappaB, respectively, and
SCF induced MIP-1beta release was mediated by ERK
Rådinger et al., J Immunol 2011
:
The decrease in stem cell factor (SCF) mediated survival in the GSK3ß knockdown HuMCs was reflected by enhancement of SCF withdrawal induced apoptosis, as determined by Annexin V staining and caspase cleavage, and this was associated with a pronounced reduction in
SCF mediated phosphorylation of Src homology 2 domain containing phosphatase 2 and
ERK1/2 and reduced expression of the antiapoptotic proteins Bcl-xl and Bcl-2