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IL21 — MMP1
Text-mined interactions from Literome
Meisser et al., Mol Hum Reprod 1999
:
The aim of this study was to determine the
effects of tumour necrosis factor alpha (TNF),
interleukin-1 alpha (IL-1alpha), macrophage colony stimulating factor ( MCSF ) and transforming growth factor beta ( TGFbeta ) on the secretion of
matrix metalloproteinases ( MMP ) , human chorionic gonadotrophin ( HCG ) and fetal fibronectin ( fFN ) by purified first trimester cytotrophoblastic cells (CTB) in vitro
Ray et al., Arthritis Rheum 2003
(Osteoarthritis) :
Overexpression of SAF-1 in OA chondrocytes increased the expression of the MMP1 promoter, and interference of endogenous SAF-1 activity by antisense SAF-1 messenger RNA inhibited
interleukin-1 mediated
MMP1 promoter activity
Sun et al., Connect Tissue Res 2003
(Arthritis, Rheumatoid) :
Furthermore, the
induction of the
MMP expression and activities by
interleukin-1 was suppressed by the oscillatory shear
Monteleone et al., Gut 2006
(Colitis, Ulcerative...) :
To investigate whether
IL21 controls
MMP production by intestinal fibroblasts ...
IL21 enhances fibroblast production of MMP-1,
MMP-2 , MMP-3 and MMP-9, but not tissue inhibitors of MMP-1 and MMP-2 ...
IL21 enhances fibroblast production of
MMP-1 , MMP-2, MMP-3 and MMP-9, but not tissue inhibitors of MMP-1 and MMP-2 ...
IL21 enhances
MMP secretion without affecting gene transcription and protein synthesis ... These results suggest that fibroblasts are a potential target of IL21 in the gut and that
IL21 controls
MMP secretion by fibroblasts
Caruso et al., J Immunol 2007
(Gastritis...) :
In this study, we have examined the role of the T cell cytokine IL-21 in Hp-infected gastric mucosa and evaluated whether
IL-21 regulates
MMP production by gastric epithelial cells
Abe et al., J Nat Prod 2010
:
The effects of these new compounds on
interleukin-1ß induced production of
matrix metalloproteinase-1 (MMP-1) in human dermal fibroblasts were examined
Gotoh et al., Connect Tissue Res 2013
:
Extracellular ß-NAD ( + ) inhibits
interleukin-1 induced
matrix metalloproteinase-1 and -3 expression on human gingival fibroblasts
Langdon et al., Arthritis Rheum 1997
(Arthritis, Rheumatoid) :
Oncostatin M stimulates monocyte chemoattractant protein-1- and
interleukin-1 induced
matrix metalloproteinase-1 production by human synovial fibroblasts in vitro
Dean et al., J Biol Chem 1999
:
We have previously shown that the pyridinyl imidazole SB 203580, which inhibits it, blocks the
interleukin-1 induction of cyclooxygenase-2 (COX-2) and
matrix metalloproteinase 1 and 3 mRNAs in fibroblasts