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CDS1 — RAD50

Text-mined interactions from Literome

Moser et al., Mol Cell Biol 2000 : Rad3 coprecipitated with Cds1 expressed at endogenous amounts, a finding that supports the hypothesis that Rad3 is involved in direct activation of Cds1
Tanaka et al., Mol Cell Biol 2001 : These results strongly suggest that Rad3 dependent phosphorylation of Cds1 at threonine-11 is required for Cds1 activation and function
Harris et al., J Cell Sci 2003 : Rad4 is shown to act upstream of the effector kinases Chk1 and Cds1, as both Chk1 phosphorylation and Cds1 kinase activity require functional Rad4
Boddy et al., Mol Cell Biol 2003 : Replication checkpoint kinase Cds1 regulates recombinational repair protein Rad60 ... Cds1 activation triggers Rad60 phosphorylation and nuclear delocalization
Zhao et al., Mol Cell Biol 2003 : Fission yeast Mrc1 ( mediator of replication checkpoint 1 ) is an adaptor checkpoint protein required for Rad3 dependent activation of the checkpoint kinase Cds1 in response to arrest of replication forks ... Consistent with this model, the T645 region of Mrc1 effectively substitutes for the T11 region of Cds1 that is thought to be phosphorylated by Rad3 and to mediate FHA dependent oligomerization of Cds1
Zhao et al., J Biol Chem 2004 : In the fission yeast Schizosaccharomyces pombe, Mrc1 is a replication checkpoint adaptor protein that allows the sensor kinase Rad3-Rad26 to activate the effector kinase Cds1
Raffa et al., J Biol Chem 2006 : Rad60 Thr ( 72 ) mediates the Cds1-Rad60 interaction and is required for the Cds1 dependent phosphorylation of Rad60 in response to replication arrest
Díaz-Cuervo et al., Mol Biol Cell 2008 : On replication stress, ataxia-telangiectasia mutated/ATM/Rad3 related kinase Rad3p activates Cds1p , which phosphorylates key proteins ensuring the stability of stalled DNA replication forks