Gene interactions and pathways from curated databases and text-mining

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ICAM1 — ITGA5

Text-mined interactions from Literome

Ishibashi et al., Microb Pathog 2003 : It has also been shown that interaction of the Arg-Gly-Asp ( RGD ) site of filamentous hemagglutinin ( FHA ) with host cell very late antigen (VLA)-5 ( alpha 5 beta 1 integrin ) is required for the up-regulation of epithelial ICAM-1 expression, and that pertussis toxin ( PT ) impairs this response
Patel et al., J Clin Immunol 1995 : While activation of TE cells with IFN-gamma for 48 hr induced a greater than fivefold increase in the expression of four surface molecules ( CD38, CD54 , MHC class I, and MHC class II ), it also induced a greater than 50 % increase in the expression of 14 other surface molecules ( CD12, CD29, CD40, CD44, CD47, CD49b, CD49c, CD49e , CD55, CD66, CD87, CD104, TE4, and STE3 ) and a decrease in the expression of three molecules ( CDw65, CDw109, and STE2 )