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CASP8 — TRAF6
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
TRAF6
—
CASP8
(physical association, affinity chromatography technology)
Bidère et al., Curr Biol 2006*
-
IRef Biogrid Interaction:
TRAF6
—
CASP8
(direct interaction, fluorescent resonance energy transfer)
He et al., J Biol Chem 2006*
-
IRef Biogrid Interaction:
TRAF6
—
CASP8
(physical association, affinity chromatography technology)
He et al., J Biol Chem 2006*
-
IRef Innatedb Interaction:
CASP8
—
TRAF6
(unknown, -)
He et al., J Biol Chem 2006*
-
IRef Innatedb Interaction:
CASP8
—
TRAF6
(unknown, -)
Bidère et al., Curr Biol 2006*
Text-mined interactions from Literome
Hull et al., J Immunol 2002
:
LPS induced loss of mitochondrial transmembrane potential, cytochrome c release, and
caspase activation are all
blocked by
TRAF6-C
Conti et al., J Neurosurg 2005
(Brain Neoplasms...) :
The authors investigated the expression of NF-kappaB,
caspase 3, TRAF1, TRAF2, and TRAF associated NF-kappaB activator/TRAF interacting protein ( TANK/I-TRAF ), a
regulator of
TRAF activity, in human gliomas
Georgopoulos et al., Cell Death Differ 2006
(Urologic Neoplasms) :
Thus,
TRAF3 stabilization, JNK activation and
caspase-9 induction define a novel pathway of CD40 mediated apoptosis in carcinoma cells
Bidère et al., Curr Biol 2006
:
Caspase-8 regulation by direct interaction with
TRAF6 in T cell receptor induced NF-kappaB activation
Zhong et al., Tumour Biol 2013
(Adenocarcinoma...) :
At the same time, we explored the
effects of
TRAF6 on the expression of the following proteins : phosphor-NF-?B ( p-p65 ), cyclin D1,
caspase-3 , and matrix metalloproteinase 9 (MMP9) ... Downregulation of
TRAF6 could decrease the expression of p-p65, cyclin D1, and MMP9 and
increase the expression of
caspase-3
Peng et al., Mol Cell Biochem 2013
(Glioma) :
In addition, the
effects of
TRAF6 on the expression of phosphor-NF-?B ( p-p65 ), cyclin D1,
caspase 3, and MMP-9 were also probed