Gene interactions and pathways from curated databases and text-mining

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EGFR — PREX1

Text-mined interactions from Literome

Sosa et al., Mol Cell 2010 (Breast Neoplasms...) : Moreover, we identified the GPCR CXCR4 as a crucial mediator of P-Rex1/Rac1 activation in response to ErbB ligands
Lopez-Haber et al., Mol Pharmacol 2013 (Breast Neoplasms) : As the Janus tyrosine kinase 2 (Jak2)/signal transducer and activator of transcription 3 ( Stat3 ) pathway has been shown to be functionally associated with ErbB receptors, we asked if this pathway could mediate P-Rex1/Rac1 activation in response to ErbB ligands