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AKT2 — PPP1R3A

Pathways - manually collected, often from reviews:

• KEGG Insulin signaling pathway: AKT1/AKT2/AKT3 → PPP1CA/PPP1CB/PPP1CC/PPP1R3A/PPP1R3B/PPP1R3C/PPP1R3D (protein-protein, indirect effect)
  

Text-mined interactions from Literome

Leung et al., FEBS Lett 2006 : Rg1 increased the phosphorylation of GR, phosphatidylinositol-3 kinase (PI3K), Akt/PKB and endothelial nitric oxide synthase (eNOS) leading to increase nitric oxide ( NO ) production in human umbilical vein endothelial cell
Leung et al., J Biol Chem 2006 : In addition, the GR antagonist RU486 was able to inhibit Rg1 induced PI3K/Akt and beta-catenin activation
Liu et al., Neurochem Int 2011 : Besides, Rg1 also inhibited the activation of Akt and the extracellular signal regulated kinase 1/2 ( ERK1/2 )
Yin et al., J Mol Med (Berl) 2011 (Disease Models, Animal...) : Rg1 induced activation of PI3K/Akt also contributed to the downregulation of p38 MAPK
Wu et al., Neurochem Int 2013 : Meantime, U0126 further decreased Rg1 induced p-Akt expression