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MDM2 — S100A9

Text-mined interactions from Literome

Javelaud et al., J Biol Chem 2002 (Colonic Neoplasms) : Enhancement of p53 expression after disruption of p21 ( WAF1 ) resulted from a stabilization of p53, which correlated with an increased expression of the tumor suppressor p14(ARF) , an inhibitor of the ubiquitin ligase activity of Mdm2
Rorie et al., Cancer Res 2004 (Neuroblastoma) : Western blot analysis revealed that whereas MDM2 gene expression does not change, p14(ARF) , a negative protein regulator of MDM2 , increases
Alt et al., J Biol Chem 2005 : Mdm2 bound to the Mre11-Nbs1-Rad50 complex in primary cells and in cells containing inactivated p53 or p14/p19ARF , a regulator of Mdm2
Hopkins-Donaldson et al., Neoplasia (New York, N.Y.) 2006 (Mesothelioma...) : p53 was also activated by : 1 ) inhibition of MDM2 ( using nutlin-3 ) ; 2 ) transient overexpression of p14(ARF) ; and 3 ) targeting of survivin using antisense oligonucleotides