Ohtsuka et al., Diabetologia 2006
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We therefore examined the role of PREB in insulin gene expression ... To analyse the effects of PREB on insulin gene transcription, we employed the luciferase reporter gene assay and electrophoretic mobility shift assay ( EMSA ) ... These results demonstrate that PREB may contribute to the regulation of insulin gene transcription and insulin secretion in response to glucose stimulation
Miyai et al., J Endocrinol Invest 2011
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Previously, we have reported that PREB plays an important role in glucose mediated insulin gene expression in pancreatic ß cells