Gene interactions and pathways from curated databases and text-mining

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INS — PLN

Text-mined interactions from Literome

Ouwens et al., Diabetologia 2005 : Insulin mediated phosphorylation of phospholamban , a critical regulator of myocardial contractility, was decreased in HFD-hearts ( p < 0.05 )
Abdallah et al., Cardiovasc Res 2006 : Insulin increased phosphorylation and activity of eNOS and augmented phospholamban phosphorylation in reoxygenated cardiomyocytes
Ablorh et al., Clin Toxicol (Phila) 2009 (Shock, Cardiogenic) : We used immunoblots to determine whether inotropic and lusitropic effects of high-dose insulin ( HDI ) in cardiogenic shock, induced by a beta-blocker ( BB ) or a calcium channel blocker ( CCB ), are mediated by phosphorylation of phospholamban (PLB)