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AKT3 — GCLC

Text-mined interactions from Literome

Kim et al., J Pharmacol Exp Ther 2004 : The phosphatidylinositol 3-kinase (PI3K) inhibitors, wortmannin and LY294002 [ 2- ( 4-morpholinyl ) -9-phenyl-4H-1-benzopyran-4-one ], dominant negative Akt , or rapamycin, an inhibitor of mTOR ( mammalian target of rapamycin ) and ribosomal p70 S6 kinase (p70S6K) phosphorylation, inhibited the insulin mediated increase in GCLC protein and GSH levels
Kimura et al., Neuroscience 2009 : Inhibitors of PI3K ( LY294002 ), Akt ( Akt-I ), and mTOR ( rapamycin ) reduced the GLP-1 induced GCLc upregulation and its protection against MG-induced PC12 apoptosis