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ROCK2 — RUNX2
Text-mined interactions from Literome
Khatiwala et al., J Bone Miner Res 2009
(MAP Kinase Signaling System) :
Inhibition of RhoA,
ROCK , or the MAPK pathway
diminished RUNX2 activity and delayed the onset of osteogenesis as shown by altered osteocalcin ( OCN ) and bone sialoprotein ( BSP ) gene expression, alkaline phosphatase (ALP) activity, and matrix mineralization
Prowse et al., PloS one 2013
:
ROCK inhibition
increased nuclear translocation of
Runx2 independent of surface roughness