Gene interactions and pathways from curated databases and text-mining

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IL1R1 — IRF6

Text-mined interactions from Literome

Penton-Rol et al., J Immunol 1999 : The present study was designed to investigate the effect of bacterial LPS on IL-1R in human monocytes
Beckman et al., Vet Immunol Immunopathol 2000 : LPS had little effect on type 1 IL-1R expression in MNC, whereas, it strongly up-regulated type 1 IL-1R expression in PMNs. Co-incubation of PMNs with LPS and bovine recombinant IL-1beta had little additional effect on type 1 IL-1R expression
Pournajafi Nazarloo et al., J Neuroimmunol 2003 : In an attempt to define the possible role of corticotropin releasing hormone (CRH) on lipopolysaccharide (LPS) induced type I interleukin-1 receptor ( IL-1R1 ), IL-1alpha, and IL-1beta mRNAs in the pituitary, adrenal gland and spleen, we used CRH-deficient ( knockout, KO ) mouse in this study
Huang et al., Nat Immunol 2004 : MEKK3 forms a complex with TRAF6 in response to IL-1 and lipopolysaccharide (LPS) but not CpG, and is required for IL-1R- and TLR4 induced IL-6 production
Marquette et al., Psychoneuroendocrinology 1994 : These results suggest that peripheral macrophages play an important role in the LPS induced modulation of central IL-1R
Gabellec et al., J Neuroimmunol 1996 : These results indicate a LPS induced stimulation of IL-1 receptors mRNAs in the brain and a differential expression of IL-1R1 and IL-1R2 transcripts in brain and immune tissues
Panja et al., J Immunol 1998 (Inflammation...) : Expression of IL-1R and IL-6R was enhanced by LPS and IFN-gamma