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PAQR3 — RAF1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Feng et al., Proc Natl Acad Sci U S A 2007
(MAP Kinase Signaling System) :
Through interaction with Raf-1,
RKTG changes the localization of Raf-1 from cytoplasm to the Golgi apparatus, blocks EGF stimulated Raf-1 membrane translocation, and
reduces the interaction of
Raf-1 with Ras and MEK1
Luo et al., Biochem J 2008
:
Taken together, these findings suggest that
RKTG is a type III membrane protein with its N-terminus facing the cytosol and multiple sequences are
responsible for its localization at the Golgi apparatus and
Raf-1 interaction