Manna et al., J Biol Chem 2011
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The PIP3 increase is mediated by PI3K activation and inhibition of PTEN but not of SHIP2
Visser et al., PloS one 2013
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Chemical inhibition of PTEN restored PIP3 signaling, as measured by Akt activation, Rac1 activation, actin uncapping, neutrophil polarization and chemotaxis in response to fMLP-stimulation, even in the presence of Msp