Gene interactions and pathways from curated databases and text-mining

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PRKACB — VAMP2

Pathways - manually collected, often from reviews:

  • KEGG Salivary secretion: PRKACA/PRKACB/PRKACG/PRKX → VAMP2 (protein-protein, indirect effect)

Text-mined interactions from Literome

Yoshida et al., J Neurosci 2005 : Consistently, constitutively active PKA or CREB stimulated VAMP2-EGFP puncta formation
Chen et al., Proc Natl Acad Sci U S A 2011 (Synaptic Transmission) : The tomosyn-SNARE interaction is regulated by protein kinase A (PKA) , an enzyme implicated in learning and memory, suggesting tomosyn could be an important effector in PKA dependent synaptic plasticity