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BMP2 — YY1

Text-mined interactions from Literome

Kurisaki et al., Mol Cell Biol 2003 : YY1 represses the induction of immediate-early genes to TGF-beta and BMP , such as the plasminogen activator inhibitor 1 gene ( PAI-1 ) and the inhibitor of differentiation/inhibitor of DNA binding 1 gene (Id-1) ... Moreover, downregulation of endogenous YY1 by antisense and small interfering RNA strategies results in enhanced transcriptional responses to TGF-beta or BMP ... In contrast, overexpression or knockdown of YY1 does not affect growth inhibition induced by TGF-beta or BMP
Lee et al., Development 2004 : SMAD mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6 dependent chick Nkx2.5 enhancer