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LRP1 — TNF

Text-mined interactions from Literome

Campana et al., J Neurosci 2006 (Sciatic Neuropathy) : Endogenously produced tumor necrosis factor-alpha (TNF-alpha) was mostly responsible for the increase in LRP-1 expression ; this activity was reproduced by direct injection of TNF-alpha into injured nerves in the TNF-alpha gene knock-out mouse
Tucker et al., Am J Respir Cell Mol Biol 2012 : These studies indicate that TNF-a and IL-1ß regulate LRP-1 in PMCs and that LRP-1 thereby contributes to a range of pathophysiologically relevant responses of these cells
Zang et al., Horm Metab Res 2013 : In contrast, LRP16 overexpression increased TNF-a secretion, suppressed glucose uptake, and attenuated 3T3-L1 cell differentiation
Stein et al., J Natl Cancer Inst 1997 (Colonic Neoplasms) : In this study, we examined the effects of tumor necrosis factor-alpha on MRP and LRP gene expression in the same colon carcinoma cells ... The effects of tumor necrosis factor-alpha on MRP and LRP messenger RNA expression were evaluated by means of reverse transcription and the polymerase chain reaction ; effects on MRP and LRP protein expression were examined by use of specific monoclonal antibodies and flow cytometry ... In transfected cells, the endogenous production of tumor necrosis factor-alpha reduced LRP gene expression ( both messenger RNA and protein ) and increased MRP gene expression ( both messenger RNA and protein ), regardless of cell type