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PPARA — SMAD3

Text-mined interactions from Literome

Reka et al., Mol Cancer Ther 2010 (Lung Neoplasms...) : Activation of PPAR-? inhibits TGF-ß induced Smad transcriptional activity but had no effect on the phosphorylation or nuclear translocation of Smads
Gong et al., Am J Physiol Lung Cell Mol Physiol 2011 (Anoxia) : These data provide strong evidence that activation of TGF-ß/Smad signaling, via transcriptional suppression of PPAR-? expression, mediates chronic hypoxia induced downregulation of PPAR-? expression in lung