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FAS — RNF19A
Text-mined interactions from Literome
Brenner et al., Cell Death Differ 1998
:
Here, we demonstrate that
Fas receptor triggered activation of the acidic sphingomyelinase, consumption of sphingomyelin, release of ceramide, and subsequent activation of JNK and
p38-K are
regulated by caspases
Ivanov et al., Oncogene 2000
(Melanoma) :
Forced expression of a dominant negative form of
p38 ( p38-ASP ) or treatment with p38 pharmacological inhibitor, SB203580,
increases NF-kappaB activity,
Fas expression and the levels of UVC induced apoptosis in late stage melanoma cells
Park et al., Mol Cancer Ther 2009
(Carcinoma, Renal Cell) :
GST-MDA-7 killing was, in parallel, dependent on inactivation of extracellular signal regulated kinase 1/2 and on
CD95 induced
p38 mitogen activated protein kinase and c-jun NH ( 2 ) -terminal kinase-1/2 signaling
Juo et al., Mol Cell Biol 1997
:
In this study
Fas activated the stress-responsive mitogen activated protein kinases,
p38 and JNK, within 2 h in Jurkat T lymphocytes but not the mitogen-responsive kinase ERK1 or pp70S6k