Gene interactions and pathways from curated databases and text-mining

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ARG2 — IRF6

Text-mined interactions from Literome

Bernard et al., Surgery 2000 (Wounds and Injuries) : Macrophage arginase activity increased in vitro in response to catecholamines or LPS ( P < .05 ) ... Trauma or LPS alone increased splenic arginase activity in vivo ( P < .05 ) ... Propranolol did not alter LPS induced splenic arginase activity but did significantly reduce trauma induced splenic arginase activity ( P < .05 )
Klasen et al., Br J Pharmacol 2001 : 5. Two different inhibitors of the NF-kappa B-pathway also prevented LPS induced increase in arginase activity ... 7. In rat AM Phi glucocorticoids inhibit LPS induced up-regulation of arginase activity, an effect which may contribute to the beneficial effects of glucocorticoids in the treatment of inflammatory airway diseases
Morrison et al., J Immunol 2002 : Stimulation of cells with IFN-gamma and LPS blocks the ability of MSP to induce arginase activity
Braulio et al., Am J Physiol Endocrinol Metab 2004 (Endotoxemia) : Although LPS did not affect total Arg production, de novo Arg production decreased after 12 h
Sosroseno et al., Oral Microbiol Immunol 2006 : The effect of cAMP analog or forskolin on arginase activity in the presence or absence of A. actinomycetemcomitans LPS was blocked by the PKA inhibitor ( KT5720 ) ... The results of the present study suggest that A. actinomycetemcomitans LPS may stimulate arginase activity in murine macrophages ( RAW264.7 cells ) in a cAMP-PKA dependent pathway
Lee et al., Mol Cells 2013 : Arginase II is localized in mitochondria of macrophage cells, and the expression of arginase II was increased by lipopolysaccharide (LPS)
Ryan et al., J Immunol 1981 : LPS activation of murine macrophage metabolism and arginase production may be mediated by products of B lymphocytes
Ryan et al., Am J Pathol 1980 : Fetal calf serum and normal mouse serum enhance macrophage arginase levels in the presence and absence of lipopolysaccharide (LPS)
Wang et al., Biochem Biophys Res Commun 1995 : In view of studies showing that not only nitric oxide synthase (NOS) activity but arginase activity is induced in rodent macrophages by lipopolysaccharide (LPS) , the objective of this study was to investigate the co-induction of these two enzymes and to ascertain whether common mechanisms are involved
Corraliza et al., Biochim Biophys Acta 1997 : In contrast, suppressors of NOS synthesis like protein kinase C inhibitors and calmodulin antagonists ( W7 ), or NO activators ( A23187 ) have no effect on the induction of arginase by LPS