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CASP3 — PRKCA
Text-mined interactions from Literome
Okuda et al., Oncogene 1999
(Adenocarcinoma...) :
Furthermore, vaccinia virus mediated overexpression of
PKCalpha strongly
increased CPP32 activity in the detached MKN45 and MKN74 cells, and augmented anoikis, however it had little effect on viability and CPP32 activity in the attached cells
Gopee et al., Cell Biol Toxicol 2004
:
The aim of current study was to investigate the
effect of
PKCalpha activation by FB1 on NF-kappaB activation and subsequently on TNFalpha gene expression and
caspase 3 induction in LLC-PK1 cells
Zhang et al., Cancer Chemother Pharmacol 2005
(Melanoma, Experimental) :
These results indicate that quercetin induced apoptosis of murine melanoma B16-BL6 cells by injuring their mitochondria, increasing the activity of
caspase-3 ,
inhibiting the expression of Bcl-2 and
PKC-alpha , and inducing the translocation of PKC-delta
Chen et al., J Neurochem 2009
(MAP Kinase Signaling System) :
Simultaneous inhibition of
PKCalpha and beta and MAPK abolished VP-induced Bad phosphorylation, but it only partially
prevented caspase 3 inhibition