Ji et al., Yao Xue Xue Bao 2009
:
In addition, TLR4 blocker partially antagonized the effect of Ang II on MPO activity in RAW264.7 cells, and fenofibrate potentiated the inhibitory effect
Ji et al., Nan Fang Yi Ke Da Xue Xue Bao 2009
:
Rosiglitazone downregulates Ang II-induced TLR4 expression in RAW264.7 cells and inhibits MPO secretion possibly by interfering with TLR4 to relieve the inflammatory reaction, which may be one of its anti-atherosclerotic mechanisms